Cytokine absorption during human kidney perfusion reduces delayed graft function–associated inflammatory gene signature
نویسندگان
چکیده
منابع مشابه
Pulsatile perfusion reduces the incidence of delayed graft function in expanded criteria donor kidney transplantation.
The use of expanded criteria donors (ECD) has been proposed to help combat the discrepancy between organ availability and need. ECD kidneys are associated with delayed graft function (DGF) and worse long-term survival. The aim of this study is to evaluate the impact of pulsatile perfusion (PP) on DGF and graft survival in transplanted ECD kidneys. From January 2000 to December 2003, 4618 ECD ki...
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Late allograft failure is characterized by cumulative subclinical insults manifesting over many years. Although immunomodulatory therapies targeting host T cells have improved short-term survival rates, rates of chronic allograft loss remain high. We hypothesized that other immune cell types may drive subclinical injury, ultimately leading to graft failure. We collected whole-genome transcripto...
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INTRODUCTION Delayed Graft Function (DGF) is a common complication of renal transplants and the long-term relation between DGF and survival of patients and grafts is not well established. METHODS This is a historical cohort study of transplanted patients in Taleghani Hospital of Shahid Beheshti University in Iran between 1994 and 2010. Patients who required dialysis during the first week afte...
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ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2020
ISSN: 1600-6135,1600-6143
DOI: 10.1111/ajt.16371